Products
7,8-Dihydroxyflavone
Use and description |
| 7,8-DHF mimics the effects of brain-derived neurotrophic factor (BDNF) in the brain by activating the tropomyosin-related kinase B (TrkB) receptors .The therapeutic potential of BDNF is restricted due to its short half-life (less than 10 minutes) and its inability to cross the blood-brain barrier because of its large size. Unlike BDNF 7,8-DHF is able to penetrate the blood-brain barrier and enter the central nervous system (CNS) . 7,8-DHF also increases the production of Nrf2. Nrf2 increases antioxidants enzymes such as heme oxygenase 1 (HO-1) and also enzymes that repair DNA (8-oxoguanine DNA glycosylase-1 - OGG1) |
Physical Characters and Index |
Product Name:7,8-Dihydroxyflavone Other name:7,8-DHF CAS:38183-03-8 Molecular Formula:C15H10O4 Molecular Weight:254.24 Purity:99% Appearance:Yellow or tan powder. Melting point:243-246°C Boiling point:494.4±45.0 °C(Predicted) Storage conditions:Inert atmosphere,Room Temperature |
