Use and description |
Secatinib is a potent Src inhibitor with IC50 of 2.7nM. It also effectively acts on c-Yes, Fyn, Lyn, Blk, Fgr and LcChemicalbookk; it has a slightly lower activity on Abl and EGFR (L858R and L861Q). Secatinib is the first inhibitor of the Src pathway in human tumor tissues. |
Physical Characters and Index |
English name: LOXO-292 CAS number: 2152628-33-4 Molecular formula: C29H31N7O3 Molecular weight: 525.6 Density:1.36±0.1 g/cm3(Predicted) |